Restek GCxGC Columns for Comprehensive Two-Dimensional Gas Chromatography
- Wide range of stationary phases offers orthogonal separations.
- High thermal stability maximizes system ruggedness and sensitivity.
- Unrivaled column inertness for accurate analysis of active compounds.
- 0.15, 0.18, and 0.25 mm ID formats accommodate varying sample capacities, speeds, and detectors.
- Secondary columns come in convenient 2 m lengths for economical method development.
Comprehensive two-dimensional gas chromatography, or GCxGC, is a powerful multidimensional GC technique that combines two independent separations to accurately analyze highly complex samples. GCxGC involves two columns with differing stationary phase selectivity (orthogonal) that are press-fitted together in series and separated by a modulator. The first (primary) column performs an initial separation, and its effluent is continually focused and “injected” in defined cycles by the modulator onto the second (secondary) column, where another separation occurs. By choosing a secondary column that is orthogonal (has different selectivity) to the primary column, it is possible to separate and identify analytes that cannot be separated by the primary column. And by keeping the secondary column very short, it is possible to maintain the separation produced by the primary column. Results generated through a series of high-speed chromatograms are plotted as a contour plot, sometimes known as a retention plane (column 1 time x column 2 time).
Restek has been performing comprehensive two-dimensional gas chromatography since its commercial inception. Our Innovations lab boasts multiple instruments dedicated to GCxGC applications, and we are continually exploring new application areas—including environmental, food safety, petroleum, forensics, fragrance, natural products, tobacco, metabolomics, and dietary supplements.
Restek GCxGC secondary columns can be matched with any Restek Rtx or Rxi primary column to create the perfect orthogonal separation for your application. Visit our GCxGC column combination guide to get started. For further assistance with column selection, method development, or anything else related to comprehensive two-dimensional gas chromatography, contact us or your Restek representative today!
Determining Pesticides in Dietary Supplements with QuEChERS Extraction, Cartridge SPE, and GCxGC-TOFMS
The novel approach used here combines QuEChERS extraction, cartridge SPE cleanup, and GCxGC-TOFMS analysis, resulting in good recoveries for a wide range of pesticides in dietary supplements. Matrices include dandelion root, sage, and a multi-herb finished product.
Guest editor Dr. Phil Marriott tells us the three primary contributions ascribed to GCxGC are greater separation capacity, greater sensitivity, and a data presentation that permits identification of related compounds based on the molecular properties that control retention. The most significant advantage is separation power: to be able to resolve many more compounds immediately enables a much more complete ‘picture’ of the composition of a sample.
Restek is your one source for 2D gas chromatography! Also known as GCxGC, 2D gas chromatography is a powerful multidimensional GC technique that combines two independent separations to accurately analyze highly complex samples. By choosing a primary and a secondary column with differing (orthogonal) stationary phases, it is possible to identify analytes using comprehensive two-dimensional gas chromatography that simply cannot be separated through standard one-dimensional GC.
Restek GCxGC Columns: Your one source for 2D gas chromatography! GCxGC is a powerful multidimensional GC technique that combines two independent separations to accurately analyze highly complex samples. By choosing a primary and a secondary column with differing (orthogonal) stationary phases, it is possible to identify analytes using comprehensive two-dimensional gas chromatography that simply cannot be separated through standard one-dimensional GC.